Overall these alterations in metabolism pathways resulted in a substantial reduction in the levels of metabolites such as aspartate, asparagine, glutamine, histidine, N-formimino-glutamate, sarcosine, and ethanolamine phosphate in LC patients ( Figure 4B , Supplementary Figure 3B )
& Kane, L
The other patient initially underwent transsphenoidal surgery because of visual disturbance, but endocrinological examinations suggested possible relationships with previous ovarian hyperstimulation
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In the control group (P0), where 106 oocytes were vitrified without GSH, the survival rate was (54.011.3)% ( n =56), (15.34.6)% ( n =16) with observed defects including zona pellucida fracture, (17.95.9)% ( n =18) with cytoplasm shrinkage, and (14.34.3)% ( n =16) with other abnormalities
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