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Key notes: Deconvolution: Software (e.g
L et al., 2014)
Weight loss timelines vary depending on individual factors such as starting weight, activity level, and consistency with treatment
Therefore, it is necessary to conduct more studies on hypoxia-tolerant species and antioxidase-related genes to better understand the adaptive mechanisms of hypoxia-tolerant mammals
The Endocrine Society's 2024 clinical practice guideline on pharmacological management of obesity recommends tirzepatide as a first-line pharmacotherapy option for adults with BMI 30 or BMI 27 with weight-related complications
