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27 and Supplementary Figs
This summer, an FDA advisory committee will consider allowing pharmacies to compound and sell seven unapproved peptides, including BPC-157
For patients with obesity and comorbidities (type 2 diabetes, hypertension, sleep apnea), referral to obesity medicine specialists or registered dietitians is appropriate for comprehensive management
When a drug introduces a genuinely new mechanism of action, the initial compound patents typically cover not only the specific molecule but the broader chemical genus from which it was selected
Patients with polycystic ovary syndrome (PCOS) may experience indirect benefits from tirzepatide through weight reduction and subsequent improvements in insulin resistance, though this is not an FDA-approved indication and specific studies in this population remain limited
A decrease in HbA1C of less than 0.5% has not been shown to correlate with improvements in the incidence of diabetic complications [13, 14]
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