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Contraindicated in people with a history of liver or kidney disease, as it may put additional strain on these organs

The most successful patients view medication as one component of comprehensive lifestyle transformation rather than a standalone solution

Similarly, the impact of renal or hepatic impairment on BPC-157 pharmacokinetics remains unexplored, though the peptide's metabolism to amino acids and apparent wide therapeutic window suggest limited risk even with reduced clearance

doi: 10.3389/fnmol.2024.1441575 10 BirbenESahinerUMSackesenCErzurumSKalayciO

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The comprehensive metabolic profile was reviewed by physicians and compared to known reference ranges