Changes in lipid pattern
The American Diabetes Association and European Association for the study of Diabetes consensus guideline recommends that, in people with type 2 diabetes and established atherosclerotic cardiovascular disease, treatment for hyperglycaemia should be diet, lifestyle change and metformin, followed by, if this does not achieve target HbA 1c levels, an agent proven to reduce cardiovascular mortality risk (Davies, 2018)
Progressive proximal muscle weakness (affecting shoulders and hips more than hands and feet) may indicate an inflammatory myopathy or other serious neuromuscular condition that requires investigation beyond simply attributing symptoms to GLP-1 therapy
Stable blood sugar levels can help prevent the rollercoaster of hunger and cravings, making it easier to stick to a healthy diet
If my skin feels comfortable after rinsing, thats the win
Additionally, if someone has underlying gastrointestinal slowing issues, like chronic constipation or slow stomach emptying, Wegovy or Zepbound would likely worsen those issues