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Moreover, NAMPT activity is crucial for the beneficial effects of calorie restriction, including improved oxidative stress management, mitochondrial biogenesis, and metabolic adaptation, as reported in a study involving Sprague-Dawley rats 213

Polymorphism in glutamate-cysteine ligase modifier subunit gene is associated with impairment of nitric oxide-mediated coronary vasomotor function

Although the mean Hcy level is higher in the group with MTHFR TT genotype, it is not statistically significant

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10.1016/j.abb.2007.05.001 Arch

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