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What about patients
Nutrition 16 : 843857
Ergothioneine accumulates in mitochondria and provides stable, long-lasting protection there complementing glutathione's short-term reactivity
Pre-existing risk factors : Individuals with established osteoporosis, previous fragility fractures, advanced age (particularly postmenopausal women), low baseline BMI, or those taking medications that affect bone metabolism (such as corticosteroids) may be more susceptible to bone density changes during weight loss
Polyphenol-Rich Foods Polyphenol-rich foods like berries, dark chocolate, and green tea contain bioactive compounds that may help prolong natural GLP-1 activity by supporting gut microbiota and metabolic pathways linked with hormone regulation
Several have active or recent FDA actions, so vetting matters
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