The clinical data indicate that slower escalation schedules reduce the severity of nausea and vomiting
But these are still under way and as yet, the product has not been regulated for use
Below is a snapshot of some supporting research: In one very small study on five people with mild to moderate Parkinsons disease and three controls, a high dose of NAC (a total of 6,000 mg/day taken orally which diminished the bioavailability of the dose) for a period of 4 weeks led to an increase of cysteine levels and antioxidant measures (GSH/GSSGa ratio of the reduced to oxidized glutathione which relates to oxidative stress with higher ratio levels associated with healthier cellsand catalase), but it did not demonstrate any improvement in the oxidative stress measurements (4HNE and MDA) nor did it increase the level of glutathione in the brains
With adequate protein intake (80-100g daily minimum, ideally 1g per pound of lean body mass), lean tissue preservation was excellent across male participants
Effect of L-carnitine on oxidative stress and platelet activation after major surgery
Patients who rush to full dose on the first injection report GI reactions at nearly twice the rate of those who titrate slowly