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It is also possible that mutation of S2 site residues could alter indirectly a putative cryptic binding site at the oligomeric interface especially as these mutants affect oligomerisation in our cell-based assays (Supplementary Fig
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Vandepol, S
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SLC25A22 achieves this by utilizing NADPH and stimulating the activity of the enzyme SCD/SCD1 (stearoyl-CoA desaturase) [102]
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