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Weigert et al., 2010)
A 2025 systematic review screened 544 articles and included 36 studies 35 preclinical (animal) and only 1 clinical and concluded plainly that no clinical safety data were found (Vasireddi et al., 2025, HSS Journal)
Secondly, our study not only investigated the associations of dietary vitamin B2 intake with osteoporosis and BMD in different femoral regions, but also explored the mediation effects of serum ALP, as well as the potential targets and mechanisms regarding vitamin B2 involved in osteogenesis and osteoclastogenesis via network pharmacological analysis
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