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In one mouse study, researchers found that the peptide reduced the pain felt by the animals in their paws when placed on a mildly hot plate. The authors explained that this could be because GHK is similar in structure to cimetidine, a histamine H2 receptor antagonist sometimes given to reduce pain in certain digestive conditions
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Reference: In Silico Pharmacogenomic Assessment of Glucagon-like Peptide-1 (GLP1) Agonists and the Genetic Addiction Risk Score (GARS) Related Pathways: Implications for Suicidal Ideation and Substance Use Disorder by Alireza Sharafshah, Kai-Uwe Lewandrowski, Mark S
Consistent with a protective effect of vitamin therapy, higher plasma homocysteine levels were associated with an increased risk of new cardiovascular events in normohomocysteinemic but not in vitamin-treated hyperhomocysteinemic subjects
(PubMed) Rayman MP, Infante HG, Sargent M
