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The first patient, a woman in her 50s, received insulin and semaglutide for 4 days before a subcutaneous dose of semaglutide

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Sudden vision loss, a shower of floaters, flashes of light, or a curtain-like shadow require urgent retinal evaluation

These constraints have intensified interest in carrier-based systems that can protect peptide drugs and potentially improve absorption without relying exclusively on chemical permeation enhancers