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Blockade of IL-10 with a neutralizing antibody fully inhibited exenatide-induced -endorphin expression both in vitro and in vivo, effectively abolishing its mechanical antiallodynic effects in neuropathic rats [63]

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Mounjaro (Tirzepatide) HR at 3 years: 4.55 (95% CI: 3.436.03)

While still under investigation, these developments highlight the broad therapeutic potential of Semaglutide

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