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In the phase 1b combination trial, 37% of all reported adverse events were gastrointestinal disorders [3]
Many patients report that foods they once craved no longer appeal to them, making eating less a natural consequence rather than a forced discipline
Specific dose levels and titration schedules varied between study arms and are defined within each trial protocol
Those with diabetic retinopathy, particularly if they have type 2 diabetes with pre-existing retinopathy and experience rapid improvement in blood glucose levels, require careful monitoring
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