Its mechanism is competitive inhibition within the NNMT catalytic pocket, blocking the methyl transfer from SAM to nicotinamide
The most common thing you might notice is mild redness, tenderness, or slight swelling where the needle went in, and that usually settles quickly
Strictly restricted to Laboratory Research Purposes Only
A 2025 study in Biomolecules found that NNMT inhibitor treatment "reduces body weight, white adipose tissue mass, total cholesterol, and adipocyte size in obese mice." These changes suggest cardiovascular benefit beyond simple weight loss
Researchers and laboratory professionals must follow all applicable institutional, local, state, and federal regulations governing the handling of research compounds
no certificate is currently published for 5-amino-1MQ, and the certificate for the lot supplied is available on request to [email protected]