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They damage cell membranes, proteins, and DNA
This can help them tolerate oxidative stress, maintain growth and neutralize some therapeutic compounds
Int.J Cosmet.Sci 2011;33(6):519-526
SSG critically modulates diverse cell death modalities (apoptosis, autophagy, pyroptosis, etc.) by altering protein conformation, membrane integrity and mitochondrial function, often amplifying inflammatory cascades (31)
By moving Nrf2 to the nucleus and initiating Nrf2/ARE signaling, SGLT2 Is lower oxidative stress and decrease fibrosis (Li et al., 2019)
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