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Ongoing support Follow-ups, adjustments, and answers are available when you need them

Physical activity may alter the secretion of signaling proteins from skeletal muscles [20]

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Post-Surgical Care: Patients who have undergone gastrointestinal surgeries, such as gastrectomies or ileal resections, may face challenges in absorbing B12 from food due to changes in the digestive process

However, our included studies intervening with a dosage higher than 2000mg/d seemed to show more benefit to patients [9,10], while one subgroup [9] with 1500mg/d showed less reduction in VAS (p value not provided)

Most patients begin with a weekly loading phase for 48 weeks, followed by monthly maintenance, with no downtime