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The maximal HbA1c-lowering effects of empagliflozin and metformin have been reported as 0.8% and 1.8%, respectively [88], which correspond to estimated reductions in DR risk of about 25% and 56% based on the UKPDS finding that each 1% decrease in HbA1c reduces DR risk by 31% [48, 54]
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Rathinam, R., Ghosh, S., Neumann, W
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