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And GLP-1 medications produce rapid, substantial weight reduction, with clinical trial participants losing an average of 13.6 kg on semaglutide and up to 25% body weight in the SURMOUNT 3 tirzepatide trial
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McDonough AA, et al
Smitka K, Papezova H, Vondra K, Hill M, Hainer V, Nedvidkova J (2013) The Role of Mixed Orexigenic and Anorexigenic Signals and Autoantibodies Reacting with Appetite-Regulating Neuropeptides and Peptides of the Adipose Tissue-Gut-Brain Axis: Relevance to Food Intake and Nutritional Status in Patients with Anorexia Nervosa and Bulimia Nervosa
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