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Takeaways Acanthosis nigricans is a skin disorder that may happen in otherwise healthy people but often shows up in people with obesity, prediabetes, or diabetes

Two key enzymes are implicated in PUFA-PE synthesis, including acyl-CoA synthetase long-chain family member 4 (ACSL4) and lysophosphatidylcholine acyltransferase 3 (LPCAT3) [75]