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Cagrilintide 4.5 mg produced 10.8% mean weight loss at 26 weeks, comparable to liraglutide 3.0 mg
Research has demonstrated that peptide-based therapies can effectively reduce inflammation and alleviate symptoms in patients with chronic conditions
Since D2HG and L2HG are indistinguishable in standard LC-MS, to determine which 2HG enantiomer(s) is affected, we adapted a chiral N-(p-toluenesulfonyl)-L-phenylalanyl chloride (TSPC) derivation followed by liquid chromatography with tandem mass spectrometry (LC-MS/MS) analysis 24,40
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