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Whilst many symptoms improve with appropriate B12 treatment, not all resolve completely, especially if neurological damage was severe or prolonged before treatment commenced

Insert needle at 45-degree angle into the fat layer

The value of another blood test, holotranscobalamin (HoloTC), decreases with vitamin B12 deficiency

However, several groups are at high risk of deficiency and may benefit significantly from regular injections or supplementation

These are typically intramuscular injections starting with high doses weekly, then switching to monthly 1,000 mcg doses for the rest of a patients life (No Stomach for Cancer, 2023)

References Minogue SC, Sun DA (2005)