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In diet-induced obese (101, 129) or non-obese (130) mice, FGF21 or an FGF21 analog reduces expression of lipogenic genes, including SCD1 , FASN , and/or SREBF1 , a master regulator of the lipogenic transcriptional network that is overexpressed on a high-fat diet
& Okuno, M
Dosing tiers: Administer two to three hours before intended sleep time, not immediately at bedtime
Mitochondrial GSTs are known as the kappa class in mammals and are mostly found in the mitochondrial matrix [60] and peroxisomes [61]
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