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Stability varies by study design
TLR1, TLR2 and TLR4 activation results in augmented mitochondrial ROS production following recruitment of mitochondria to macrophage phagosomes, leading the way to increased mitochondrial and cellular ROS generation (West et al., 2011)
Further reports of this variant in individuals with a similar phenotype may allow for this to be upgraded to a likely pathogenic variant according to ACMG guidelines
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It is not compatible with thiol compounds such as DTT and cysteine
Lysine-Proline-Valine Peptide Mitigates Fine Dust-Induced Keratinocyte Apoptosis and Inflammation by Regulating Oxidative Stress and Modulating the MPK/NF-KB Pathway
