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Blood pressure is the benefit with the largest pooled dataset behind it. Averaged across 11 randomized controlled trials, oral L-arginine lowered systolic pressure by 5.4 mmHg and diastolic by 2.7 mmHg, an effect size comparable to a single lifestyle intervention rather than a medication
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Other oxidative stress triggers include a poor diet, low physical activity, prolonged stress, and intrinsic factors, such as mitochondrial dysfunction leading to reduced adenosine 5-triphosphate (ATP) production, inflammation, and hypoxia (106, 117)
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Kuratsune H, et al
PMC 4345927
