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Research has shown these genes can be turned on via cell-signaling pathwaysthe major one being Nrf2

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doi: 10.1016/j.freeradbiomed.2022.12.105 122 HayashiSNakamuraTMotookaYItoFJiangLAkatsukaSet al

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doi: 10.3389/fendo.2023.1301093 156 De BieTHWitkampRFBalversMGJongsmaMA