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Description

(3)(cagrilintide)pH4.0(cagrilintide) (cagrilintide): 00.59.6 mg/ml 5 mM (0.74 mg/ml lL-) 24 mg/ml (HCl)pH4.0 (NaOH)pH4.0 (WFI)A total of three (3) different cagrilintide formulations were prepared, with different concentrations of cagrilintide at pH 4.0, and the composition was as follows: Cagrilintide: 0, 0.5 or 9.6 mg/ml Glutamate: 5 mM (added in the form of 0.74 mg/ml lL-glutamate) Glycerin: 24 mg/ml Hydrochloric acid (HCl), add as needed to obtain a pH value of 4.0 Sodium hydroxide (NaOH), add as needed to obtain a pH value of 4.0 Water for injection (WFI) is used as a solvent

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