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251,252 In the canonical cascade, ligand binding (e.g., Jagged1/2, DLL1/3/4) to Notch receptors (Notch14) induces a two-step proteolytic cleavage, culminating in the release of the Notch intracellular domain (NICD), a cleaved cytoplasmic signaling domain that mediates intracellular signal transduction, by -secretase
Neuroscience 277, 613
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And we know poor nutrition can lead to delayed wound healing, wound dehiscence, and hypertrophic scars. Dr
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doi: 10.1002/ptr.1957 105 YenF
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