The good news is that the body often adjusts to each new dose
Information about generic semaglutide availability is subject to change based on Health Canada approval timelines.
13 In the SURPASS-4 trial (phase III), participants taking tirzepatide showed a much lower occurrence of composite kidney endpoint (time to first occurrence of eGFR decline of at least 40% from baseline, end-stage kidney disease, death due to kidney failure, or new onset albuminuria) compared with those who received insulin glargine (HR 0.58)
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For those already taking Wegovy and have progressed to the higher dosage strengths of 1.7 mg or 2.4 mg, getting their prescription may be less problematic as these strengths are expected to be less affected by the shortage