[16] [18] These metabolites, including cyclic 3-hydroxymelatonin, N1-acetyl-N2-formyl-5-methoxykynuramine (AFMK), and N1-acetyl-5-methoxykynuramine (AMK), contribute to the broader antioxidative effects of melatonin through further redox reactions with free radicals
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If the downstream steps of glutathione synthesis cannot keep pace, due to either limited glycine availability, reduced enzymatic capacity, or energy depletion, this intermediate will accumulate
Jung, Y
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