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Induction of pyruvate carboxylase can allow tumor cells to use glucose-derived pyruvate instead of glutamine for anaplerosis, inducing a glutamine-independent growth [106-108]
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In terms of treatment duration, the incidence of adverse events within a treatment cycle (typically 4 weeks) is significantly lower compared to other time periods
Fewer variables in the research formulation can make some research questions more interpretable
Vitamin deficiency anemia
The ECAR profile (Fig
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