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Importantly, this analysis assumes some AOMs will soon be subject to the drug price negotiations implemented under the Inflation Reduction Act (IRA), which CBO estimates would reduce the price-per-user of the drugs by 32 percent after 2027

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Research shows that five GLP-1s account for 16% of the overall prescription cost for the Rx Collaborative, the largest pharmacy coalition in the U.S., after estimated rebates and discounts in Q1-Q3 of 2024, a rise from just 1% in 2020

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