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In addition, acute kidney injury (AKI) has an important impact on the occurrence and development of CKD

El envejecimiento, el estrs oxidativo o el uso de ciertos frmacos (estatinas, betabloqueantes) reducen sus niveles endgenos

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In Drosophila, the SLC25A39/40 homolog Shawn localizes to mitochondria, and its loss increases ROS accumulation, disrupts mitochondrial function, and causes progressive neurodegeneration 13

Crit Rev Biochem Mol Biol 30 : 445600

These pathway-level effects are proposed based on integrated transcriptomic and protein expression data and warrant further validation