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According to obtained results, this association can be explained by a more hostile stroma, which upon dysmetabolism additional enhances ECM deposition, enriching collagen biosynthesis and further reducing the already barely detectable immune infiltration in PDAC
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It is unclear whether this association holds true for drug-induced heart-rate acceleration
doses of SAR441255 were studied in lean to overweight individuals and, at the two highest doses tested (80 and 150 ug), fasting blood glucose levels reached a nadir within the first hour [95]
NAC may cause nausea, particularly at higher doses, and has a characteristic sulphur odour that some individuals find unpleasant
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