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Tesofensine, during its Phase II trials, led to important decreases in body weight and fat in people who are obese
This is rare but can occur with sertraline, particularly when combined with other serotonergic medications (e.g., other antidepressants, tramadol, triptans, St John's wort, or certain illicit drugs) In an emergency: Call 999 if you experience severe chest or abdominal pain, signs of a severe allergic reaction, severe confusion, high fever, or seizures Contact NHS 111 for urgent but non-emergency advice when your GP is unavailable Before starting any new medication (prescription, over-the-counter, or herbal), inform your pharmacist that you are taking both Mounjaro and sertraline
Tirzepatide might have a higher occurrence of stomach-related side effects at increased doses, making dosage an important consideration
& Elliott, D
This delay in gastric emptying results in a prolonged feeling of fullness after meals, reducing the tendency to overeat