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Step 2: Start with a lower dose

The most common side effects are gastrointestinal, including nausea, diarrhoea, and decreased appetite

Science 358 , 10191027 (2017)

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Reasons may include: Dose too low Irregular injection schedule Diet and lifestyle inconsistencies Underlying hormonal or metabolic issues If progress is slower than expected, a provider may review: Relevant labs and health markers Medication tolerance and dosing Nutrition, movement, sleep, and stress patterns Whether the care plan should continue, change, or stop This is why provider-guided monitoring can help personalize care and support safer treatment decisions