If post-meal control is the problem, address mealtime insulin or non-insulin agents rather than increasing basal indefinitely
Others may have genetic variations affecting glucagon receptor signaling or GIP pathway function
Despite incorporating gym workouts + HIIT (and no change to any other variables), my hba1c bumped up from 5.2% to 5.8%, having taken rosuvastatin 5mg/day for 4 weeks in a row I suspect this could be an amplified response in a highly insulin sensitive individual like me, with Fasting Insulin 2 and Fasting Glucose 90) In general, Rosuvastatin appears to have a dose-dependent effect on glucose metabolism for the average population (although some people dont seem to have any/much side effect even at large dose), however, for some people, even a low dose appears to significantly impair glucose homeostatis
[20] [21] People taking retatrutide alongside insulin or sulfonylureas should be particularly cautious, as alcohol can increase the risk of hypoglycaemia
IL-6 functions as a pleiotropic cytokine activating hepatic acute phase protein synthesis, promoting B-cell differentiation, and mediating systemic inflammatory responses [87]
Chew food thoroughly and eat slowly to aid digestion and reduce discomfort