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These symptoms often appear when you first start the medication or when your dose increases

465 The downregulation of GLP-1R expression may represent a significant contributory factor to the co-occurrence of hypertension and hyperglycemia

Deletion of the gene encoding ABCA1, responsible for lipidating ApoE in the CNS, resulted in an increase in A deposition (Wahrle et al., 2005) Conversely, overexpression of ABCA1 resulted in a decrease in A deposition (Wahrle et al., 2008) in amyloid mouse models, suggesting that increasing ApoE lipidation can reduce A pathology

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