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If you are currently taking any other medications, let your doctor know before choosing a suitable B12 supplement

A three way crossover study in 25 fasting healthy subjects was conducted to compare the bioavailability of the B12 nasal spray to the B12 nasal gel and to evaluate the relative bioavailability of the nasal formulations as compared to the intramuscular injection

There is also an energy consideration

Common reported effects in clinical use include mild injection site reactions with subcutaneous administration, occasional digestive changes when taken orally, and rare reports of fatigue or dizziness

Total cost for the protocol: around 50 to 80 depending on the chosen formats

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