Moreover, among the three mutants, the pgdS single mutant produced PGA with the highest molecular weight, which could be attributed to hampered endo-peptidase activity
How Alcohol Depletes Vitamin B12 Heavy drinking depletes this nutrient through a number of mechanisms: Diuretic effect Alcohol significantly increases urinary excretion of vitamin B12, which is taken from the blood and liver
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doi:10.1126/scitranslmed.add1531 [52] Hulme H, Meikle LM, Strittmatter N, et al