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[3] The scientists note that results together suggest that myostatin suppresses both basal and IGF-1-stimulated proliferation of both WAT and BAT preadipocytes, actions that are again similar to those in muscle satellite cells. Receptor Grade IGF-1 LR3, due to its speculated stability, may potentially counteract Myostatin by activating MyoD, a muscle protein normally triggered through prolonged physical strain

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Ridlon JM, Wolf PG, Gaskins HR