Those who attempt to shed pounds and maintain a healthy liver may benefit from this
92,93 However, in the latter patient population, B12 has shown some benefits when used alongside other approaches including light therapy and drugs, although these studies had some methodological weaknesses, making it difficult to interpret the results
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Mechanistically they do not overlap (GLP-1 agonists work through appetite and gastric emptying, this works on adipocyte lipogenesis and NAD+), and the mouse data specifically showed fat loss without reduced food intake, so they are not redundant