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Very common side effects (affecting more than 1 in 10 people) include: Headache Nausea Vomiting Diarrhoea Constipation Stomach pain Tiredness or weakness Indigestion Common side effects (affecting up to 1 in 10 people) include: Dizziness Bloating, wind, and burping Gastritis Heartburn or acid reflux Changes in taste Gallstones Hair loss Tingling or burning sensations Low blood sugar in people with type 2 diabetes Uncommon side effects (affecting up to 1 in 100 people) include: Low blood pressure Feeling faint when standing up Fast heartbeat Delayed stomach emptying Raised pancreatic enzyme levels Low blood sugar in people without type 2 diabetes Increased bilirubin levels, which may cause yellowing of the skin or eyes Rare side effects (affecting up to 1 in 1,000 people) include: Allergic reactions Sudden swelling Hip fracture How can I manage nausea (feeling sick)

Tirzepatide Dose Escalation Schedule and Clinical Milestones A typical tirzepatide dose escalation follows a structured timeline

37% More Weight Loss with Noom Habits More Weight Loss with Noom Habits Building healthy habits with Noom may help you lose 37% more weight while on a GLP-1.** **Based on a January 2026 analysis of 14,203 Noom GLP-1Rx Program members who actively logged their weight over a 40-week period

Please consult a qualified gastroenterologist for diagnosis and personalised treatment.

Clinical Status Human RCT | Observational | Animal | In vitro Primarily studied in preclinical and exploratory human growth hormone and appetite signaling research contexts

If you have symptoms of deficiency or risk factors such as metformin use, speak with your GP about appropriate testing and treatment