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However, the highest levels of PR and GST gene expression were associated with SA-deficiency, rather than enhanced TMV resistance ( Figures 6 and 7 ), a possible sign of excessive oxidative stress in virus-infected SA-deficient tobacco cells in later stages of pathogenesis, when HR is fully developed
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The same thing happens after bariatric surgery or any rapid weight loss
The meta-analysis also included the DEMEL trial [1], a multi-center multi-arm adaptive RCT showing no significant benefit of nightly administered melatonin, at a pharmacokinetically optimized low dose (0.3 mg), compared to placebo
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