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Glutathione levels decline measurably with age due to reduced precursor availability, which contributes to elevated oxidative stress, mitochondrial dysfunction, and impaired immune regulation

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Free Radic Biol Med 233:118131 Vahedi Raad M, Firouzabadi AM, Tofighi Niaki M, Henkel R, Fesahat F (2024) The impact of mitochondrial impairments on sperm function and male fertility: a systematic review