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10.3389/fmicb.2020.00420 77 QureshiN.LiP.GuQ
Animal Model Evidence The systemic evidence base is entirely preclinical: Pulmonary fibrosis (mouse model): Intraperitoneal GHK-Cu at 0.2-20 micrograms/g/day protected against bleomycin-induced lung fibrosis by inhibiting TGF-beta1/Smad signaling and reducing oxidative stress (PMID 31809714)
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The role of the SoxC family in neuronal development is not fully understood and it was suggested that SoxC proteins control the establishment of pan-neuronal gene expression (Bergsland et al., 2006) in contrast to proneural bHLH proteins that have been linked to the control of neuronal subtype identity (Berninger et al., 2007)
