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In patients with DKD, the expression level of messenger RNA (mRNA) encoding IL6 is positively correlated with the degree of dilatation of the thylakoid glands (Suzuki et al., 1995), which is a characteristic histologic feature of the disease (Fantuzzi et al., 1999)

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A study in obese rat showed that IF could prevent memory loss in comparison to ad libitum by regulating body metabolism (54), which offering a new sight for the advantages of IF to remit neuroinflammation

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Additionally, dihydrofolate reductase (DHFR) regenerates BH4 from BH2, thus inhibiting ferroptosis

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doi: 10.3109/01485019508987828 214 NegriPGrechiETomasiAFabbriECapuzzoA

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