FDA said that the peptide is not adequately characterized and has the potential for peptide-related impurities due to incomplete coupling reactions, truncations, or side reactions
Adipocyte-specific Gipr ablation protects mice from HFD-induced insulin resistance and hepatic steatosis, potentially by reducing circulating levels of pro-inflammatory cytokines (68)
This study first reveals that ROS-driven HIF-1-BNIP3/NIX-mediated mitophagy mitigates hypoxia-induced inflammation and apoptosis, contributing to the enhanced hypoxia adaptation observed in Tibetans
Diabetes Metab 38(1):8688 Hogan AE et al (2011) Glucagon-like peptide-1 (GLP-1) and the regulation of human invariant natural killer T cells: lessons from obesity, diabetes and psoriasis
Patients with polycythemia vera a blood disorder involving overproduction of red blood cells face additional risks since B12 stimulates red blood cell production
A wave of 2nd generation GLP-1 agonists came to market between 2014-2021, improving clinical outcomes and providing more convenient dosing and administration options