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As inflammation and oxidative stress in the vascular system drop, stiffness and plaque risk fall too, which many researchers now treat as a direct readout of true biological age rather than just a cardiology metric

Tirzepatide can make those changes more realistic by calming hunger and cravings, but it doesnt replace better food choices and movement

A 28.7% average at 68 weeks puts retatrutide in territory that only bariatric surgery has previously occupied

Its ability to protect against oxidative stress makes it vital for skin health

While weight loss surgery remains the most effective option for total weight loss and long-term maintenance, Zepbound emerges as a potentially powerful medication for those who may not be surgical candidates, require additional support post-surgery, or are initially hesitant about undergoing a surgical procedure

Moreover, adverse events leading to medication discontinuation were reported by 10% in the overall retatrutide groups (616% across groups vs