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doi: 10.3389/fphar.2025.1586231 Received 21 March 2025 Accepted 30 April 2025 Published 09 June 2025 Volume 16 - 2025 Edited by Irwin Rose Alencar de Menezes, Regional University of Cariri, Brazil Reviewed by Alaaeldin Ahmed Hamza, National Organization for Drug Control and Research (NODCAR), Egypt Mohannad A

In both studies, tesamorelin-treated patients completing the 26-week treatment period were re-randomized to blinded therapy with either daily placebo or 2 mg tesamorelin for an additional 26-week treatment period (Extension Phase) in order to assess maintenance of VAT reduction and to gather long-term safety data

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Specific metabolic rates of major organs and tissues across adulthood: evaluation by mechanistic model of resting energy expenditure